USC-OGP 2-DE database Two-dimensional polyacrylamide gel electrophoresis database

USC-OGP 2-DE database  Search by                Maps             Select Remote Interfaces [All Interfaces] SWISS-2DPAGE World-2DPAGE Portal World-2DPAGE Repository Exclude local DBs has only effect if a remote interface is selected

Searching in 'USC-OGP 2-DE database' for entry matching: P53004 USC-OGP 2-DE database:  P53004 P53004 General information about the entry View entry in simple text format Entry name BIEA_HUMAN Primary accession number P53004 integrated into USC-OGP 2-DE database on  January 17, 2017 (release 1) 2D Annotations were last modified on January 17, 2017 (version 1) General Annotations were last modified on  April 5, 2017 (version 2) Name and origin of the protein Description RecName: Full=Biliverdin reductase A; Short=BVR A; EC=1.3.1.24; AltName: Full=Biliverdin-IX alpha-reductase; Flags: Precursor;. Gene name Name=BLVRA Synonyms=BLVR, BVR Annotated species Homo sapiens (Human) [TaxID: 9606] Taxonomy Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo. References [1]   2D GEL CHARACTERIZATION Author 1., Author 2. Submitted (Mar-2011) to Current 2D PAGE maps for identified proteins How to interpret a protein PLATELET_4-7 {PLATELET 4-7} Homo sapiens (Human)   map experimental info   PLATELET_4-7 MAP LOCATIONS: SPOT OGP-0429: pI=6.06; Mw=40412 SPOT OGP-0437: pI=5.96; Mw=38579 PLATELET_5-6 {PLATELET 5-6} Homo sapiens (Human)   map experimental info   PLATELET_5-6 MAP LOCATIONS: SPOT OGP-0742: pI=5.93; Mw=35341 UVEAL_MELANOMA_3-10 {UVEAL MELANOMA 3-10} Homo sapiens (Human)   map experimental info   UVEAL_MELANOMA_3-10 MAP LOCATIONS: SPOT OGP-1203: pI=6.30; Mw=39011 SPOT OGP-1206: pI=6.27; Mw=38575 Cross-references UniProtKB/Swiss-Prot P53004; BIEA_HUMAN. 2D PAGE maps for identified proteins How to interpret a protein map You may obtain an estimated location of the protein on various 2D PAGE maps, provided the whole amino acid sequence is known. The estimation is obtained according to the computed protein's pI and Mw. Warning 1: the displayed region reflects an area around the theoretical pI and molecular weight of the protein and is only provided for the user's information. It should be used with caution, as the experimental and theoretical positions of a protein may differ significantly. Warning 2: the 2D PAGE map is built on demand. This may take some few seconds to be computed. External data extracted from UniProtKB/Swiss-Prot Extracted from UniProtKB/Swiss-Prot, release: 0.0 Entry name BIEA_HUMAN Primary accession number P53004 Secondary accession number(s) A8K747 O95019 Q86UX0 Q96QL4 Q9BRW8 Sequence was last modified on  October 10, 2002 (version 2) Annotations were last modified on  March 15, 2017 (version 166) Name and origin of the protein Description RecName: Full=Biliverdin reductase A; Short=BVR A; EC=1.3.1.24; AltName: Full=Biliverdin-IX alpha-reductase; Flags: Precursor; Gene name Name=BLVRA Synonyms=BLVR, BVR Encoded on Name=BLVRA; Synonyms=BLVR, BVR Keywords 3D-structure; Acetylation; Complete proteome; Cytoplasm; Direct protein sequencing; Metal-binding; NAD; NADP; Oxidoreductase; Phosphoprotein; Polymorphism; Reference proteome; Zinc. Copyright Copyrighted by the UniProt Consortium, see http://www.uniprot.org/help/license. Distributed under the Creative Commons Attribution-NoDerivs License Cross-references EMBL U34877; AAC35588.1; -; mRNA EMBL X93086; CAA63635.1; -; mRNA EMBL AK291862; BAF84551.1; -; mRNA EMBL AY616754; AAT11126.1; -; Genomic_DNA EMBL AC005189; -; NOT_ANNOTATED_CDS; Genomic_DNA EMBL AC004939; AAD05025.1; -; Genomic_DNA EMBL AC004985; AAP21879.1; -; Genomic_DNA EMBL BC005902; AAH05902.1; -; mRNA EMBL BC008456; AAH08456.1; -; mRNA CCDS CCDS5472.1; -; . PIR G02066; G02066; . PIR S62624; S62624; . RefSeq NP_000703.2; NM_000712.3; . RefSeq NP_001240752.1; NM_001253823.1; . RefSeq XP_011513776.1; XM_011515474.2; . RefSeq XP_016868009.1; XM_017012520.1; . UniGene Hs.488143; -; . PDB 2H63; X-ray; 2.70 A; A/B/C/D=7-296 PDBsum 2H63; -; . ProteinModelPortal P53004; -; . SMR P53004; -; . BioGrid 107113; 16; . DIP DIP-42180N; -; . IntAct P53004; 2; . MINT MINT-1212210; -; . STRING 9606.ENSP00000265523; -; . DrugBank DB00157; NADH; . iPTMnet P53004; -; . PhosphoSitePlus P53004; -; . BioMuta BLVRA; -; . DMDM 23830892; -; . OGP P53004; -; . REPRODUCTION-2DPAGE IPI00294158; -; . EPD P53004; -; . MaxQB P53004; -; . PaxDb P53004; -; . PeptideAtlas P53004; -; . PRIDE P53004; -; . Ensembl ENST00000265523; ENSP00000265523; ENSG00000106605; . Ensembl ENST00000402924; ENSP00000385757; ENSG00000106605; . GeneID 644; -; . KEGG hsa:644; -; . UCSC uc003tir.4; human; . CTD 644; -; . DisGeNET 644; -; . GeneCards BLVRA; -; . HGNC HGNC:1062; BLVRA; . HPA HPA019709; -; . HPA HPA042865; -; . HPA HPA054322; -; . MalaCards BLVRA; -; . MIM 109750; gene; . MIM 614156; phenotype; . neXtProt NX_P53004; -; . OpenTargets ENSG00000106605; -; . Orphanet 276405; Hyperbiliverdinemia; . PharmGKB PA25373; -; . eggNOG ENOG410IH7U; Eukaryota; . eggNOG ENOG4111FZX; LUCA; . GeneTree ENSGT00390000011072; -; . HOGENOM HOG000231884; -; . HOVERGEN HBG003218; -; . InParanoid P53004; -; . KO K00214; -; . OMA NMPNVGV; -; . OrthoDB EOG091G0E2N; -; . PhylomeDB P53004; -; . TreeFam TF342889; -; . BioCyc MetaCyc:HS02928-MONOMER; -; . BRENDA 1.3.1.24; 2681; . Reactome R-HSA-189483; Heme degradation; . SIGNOR P53004; -; . UniPathway UPA00684; -; . ChiTaRS BLVRA; human; . EvolutionaryTrace P53004; -; . GenomeRNAi 644; -; . PRO PR:P53004; -; . Proteomes UP000005640; Chromosome 7; . Bgee ENSG00000106605; -; . CleanEx HS_BLVRA; -; . ExpressionAtlas P53004; baseline and differential; . Genevisible P53004; HS; . GO GO:0005829; C:cytosol; IDA:HPA; . GO GO:0070062; C:extracellular exosome; IDA:UniProtKB; . GO GO:0004074; F:biliverdin reductase activity; IDA:UniProtKB; . GO GO:0008270; F:zinc ion binding; IEA:InterPro; . GO GO:0042167; P:heme catabolic process; TAS:UniProtKB; . GO GO:0055114; P:oxidation-reduction process; IDA:UniProtKB; . Gene3D 3.40.50.720; -; 1; . InterPro IPR017094; Biliverdin_Rdtase_A; . InterPro IPR015249; Biliverdin_Rdtase_cat; . InterPro IPR016040; NAD(P)-bd_dom; . InterPro IPR000683; Oxidoreductase_N; . Pfam PF09166; Biliv-reduc_cat; 1; . Pfam PF01408; GFO_IDH_MocA; 1; . PIRSF PIRSF037032; Biliverdin_reductase_A; 1; . ProDom PD040165; Biliverdin_Rdtase_cat; 1; . SUPFAM SSF51735; SSF51735; 1; .

Gateways to other related servers

• The World-2DPAGE Constellation - Entry point to the world-wide 2-DPAGE resources.
• World-2DPAGE Repository - A public repository for gel-based proteomics data linked to protein identification published in the literature.
• World-2DPAGE Portal - A dynamic portal to query simultaneously world-wide gel-based proteomics databases.
• SWISS-2DPAGE - The Geneva Two-dimensional polyacrylamide gel electrophoresis database.
• ExPASy - The resources web server of the Swiss Institute of Bioinformatics

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